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Omicron sublineage BA.2 remains a variant of concern-WHO

beatsadmin by beatsadmin
February 23, 2022
in News
Reading Time: 2 mins read
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The first consignment of COVID-19 vaccine developed by the U.S. manufacturer, Novavax, is expected to reach Germany this week, according to a spokesperson for the Health Ministry in Berlin. “We are expecting the first delivery from Monday,’’ the spokesperson confirmed on Sunday, two days after Health Minister Karl Lauterbach said that 1.4 million doses were due to arrive. The Novavax vaccine is a significant development in the fight against the coronavirus, unlike the Biontech/Pfizer and Moderna vaccines. “This is not an mRNA vaccine. Instead, it is based on classic vaccine model, with its virus-like particles containing the spike protein of the Coronavirus and an effect enhancer. “The so-called messenger ribonucleic acid (mRNA) in the mRNA vaccines delivers part of the virus’s genetic information to the human cells. With this, cells produce a protein of the pathogen, from which the body then develops immunity,” the spokesperson said. The Novavax vaccine is to be distributed among Germany’s different states, each of which will decide when to begin administering it. Some states have already announced that they would begin vaccinations with the new drug in the first week of March. The hope is that the Novavax vaccine would help boost vaccination rates by providing an alternative for those who have reservations about mRNA vaccines. However, whether it will have a broader impact on the battle against the coronavirus in Germany is unclear.
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The BA.2 virus, a sublineage of the Omicron COVID-19 mutation, should continue to be considered a variant of concern, scientists convened by the World Health Organisation (WHO) said in a statement on Tuesday.

According to WHO’s Technical Advisory group, BA.2 should also remain classified as Omicron.

SARS-CoV-2 is the virus that causes COVID-19, and the expert group meets regularly to discuss available data on transmissibility and severity of variants as well as their impact on diagnostics, therapeutics, and vaccines.

They stressed that public health authorities should continue to monitor BA.2 as a distinct sublineage of Omicron, currently the dominant variant circulating globally.

Omicron is made up of several sublineages, including BA.1 and BA.2, all of which are being monitored by WHO and partners.

BA.2 is among the most common, with reported sequences increasing in recent weeks, relative to BA.1, though global circulation of all variants is currently declining.

The experts explained that BA.2 differs from BA.1 in its genetic sequence, and that it has a growth advantage over this sublineage.

Although studies are ongoing to understand why, initial data suggest BA.2 appears inherently more transmissible than BA.1, currently the most common Omicron sublineage reported.

However, this difference in transmissibility appears to be much smaller than that between BA.1 and the Delta variant, the experts said.

Meanwhile, although BA.2 sequences are increasing in proportion relative to other Omicron sublineages, there is still a reported decline in overall cases globally.

Furthermore, while cases of reinfection with BA.2 following infection with BA.1 have been documented, preliminary data from studies show that infection with BA.1 provides strong protection against reinfection with BA.2.

WHO will continue to closely monitor the BA.2 lineage as part of Omicron.

The UN agency urged countries to remain vigilant, to monitor and report sequences, and to conduct independent and comparative analyses of the different Omicron sublineages.

Globally, there were more than 424,820,000 cases of COVID-19 as of Tuesday, and more than 5.8 million deaths, according to WHO data.

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